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Smarcb1tm1Mya
Targeted Allele Detail
Summary
Symbol: Smarcb1tm1Mya
Name: SWI/SNF related BAF chromatin remodeling complex subunit B1; targeted mutation 1, Moshe Yaniv
MGI ID: MGI:2387974
Synonyms: SNF5-, SNF5lacZ
Gene: Smarcb1  Location: Chr10:75732603-75757448 bp, - strand  Genetic Position: Chr10, 38.61 cM
Alliance: Smarcb1tm1Mya page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:68501
Parent Cell Line:  CK35 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: The gene was disrupted by replacement of exons 1 and 2 with a lacZ-PGK-neo cassette. Beta gallctosidase is expressed from this allele under the control of the endogenous promoter. (J:68501)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smarcb1 Mutation:  22 strains or lines available
References
Original:  J:68501 Klochendler-Yeivin A, et al., The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression. EMBO Rep. 2000 Dec;1(6):500-6
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory