Plcg1tm2Gcrp
Targeted Allele Detail
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| Symbol: |
Plcg1tm2Gcrp |
| Name: |
phospholipase C, gamma 1; targeted mutation 2, Graham Carpenter |
| MGI ID: |
MGI:2388142 |
| Synonyms: |
Plcg1- |
| Gene: |
Plcg1 Location: Chr2:160573230-160617680 bp, + strand Genetic Position: Chr2, 80.97 cM
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| Alliance: |
Plcg1tm2Gcrp page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:39281
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| Parent Cell Line: |
TL1/TL-1 (ES Cell)
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| Strain of Origin: |
129S6/SvEvTac
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| Allele Type: |
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Targeted (Null/knockout, Reporter) |
| Mutation: |
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Disruption caused by insertion of vector
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Mutation details: Sequence encoding the X domain and both SH3 domains were deleted by the insertion of a cassette containing both lacZ and neo. Only truncated protein was detected by Western blot analysis of MEFs derived from homozygous mutant mice. TV-II targeting vector.
(J:39281)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Plcg1 Mutation: |
48 strains or lines available
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| Original: |
J:39281 Ji QS, et al., Essential role of the tyrosine kinase substrate phospholipase C-gamma1 in mammalian growth and development [see comments]. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):2999-3003 |
| All: |
3 reference(s) |
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Analysis Tools
