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Sall1tm1Ryn
Targeted Allele Detail
Summary
Symbol: Sall1tm1Ryn
Name: spalt like transcription factor 1; targeted mutation 1, Ryuichi Nishinakamura
MGI ID: MGI:2388379
Synonyms: Sall1-del
Gene: Sall1  Location: Chr8:89753867-89770790 bp, - strand  Genetic Position: Chr8, 43.51 cM, cytoband D
Alliance: Sall1tm1Ryn page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:71242
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: The entire coding region, except for sequences encoding the 52 N-terminal amino acids, was deleted and replaced with a neomyin resistance cassette. The mutation removes all zinc finger domains from the gene. Absence of gene expression in homozygous mutant animals was verified by RT-PCR and in situ hybridization. (J:71242)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Sall1 Mutation:  78 strains or lines available
References
Original:  J:71242 Nishinakamura R, et al., Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development. Development. 2001 Aug;128(16):3105-15
All:  9 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory