About   Help   FAQ
Igf1rtm2Arge
Targeted Allele Detail
Summary
Symbol: Igf1rtm2Arge
Name: insulin-like growth factor I receptor; targeted mutation 2, Argiris Efstratiadis
MGI ID: MGI:2389580
Synonyms: Igf1rc, Igf1rlox, IGF1RLox
Gene: Igf1r  Location: Chr7:67602575-67883416 bp, + strand  Genetic Position: Chr7, 37.27 cM
Alliance: Igf1rtm2Arge page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:60711
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/SvEv
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exon 3 was flanked by a floxed neo cassette in intron 2 and a single loxP site in intron 3. (J:60711)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Igf1r Mutation:  88 strains or lines available
References
Original:  J:60711 Dietrich P, et al., Conditional mutagenesis in mice with heat shock promoter-driven cre transgenes. Mamm Genome. 2000 Mar;11(3):196-205
All:  71 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory