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Adgre1tm1(cre)Kpf
Targeted Allele Detail
Summary
Symbol: Adgre1tm1(cre)Kpf
Name: adhesion G protein-coupled receptor E1; targeted mutation 1, Klaus Pfeffer
MGI ID: MGI:2429642
Synonyms: F4/80-, F4/80-Cre, F4/80Cre
Gene: Adgre1  Location: Chr17:57665691-57790527 bp, + strand  Genetic Position: Chr17, 29.8 cM
Alliance: Adgre1tm1(cre)Kpf page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:79911
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Adgre1tm1(cre)Kpf expression driven by 1 gene
 
Mutation details: The insertion of a targeting vector replaced endogenous coding sequence with cre and neo. Northern blot and immunohistochemical analyses indicated the absence of transcript and protein in homozygous mutant mice. Recombination of a floxed reporter verified translation of a functional cre recombinase. (J:79911)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Adgre1 (mouse)
Summary of all recombinase alleles driven by Adgre1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adgre1 Mutation:  79 strains or lines available
References
Original:  J:79911 Schaller E, et al., Inactivation of the F4/80 glycoprotein in the mouse germ line. Mol Cell Biol. 2002 Nov;22(22):8035-43
All:  8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory