Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol:	Tg(Nes-cre)1Wmz
Name:	transgene insertion 1, Weimin Zhong
MGI ID:	MGI:2429684
Synonyms:	Nes8Cre, NesCre8, nestin-cre
Transgene:	Tg(Nes-cre)1Wmz  Location: unknown
Alliance:	Tg(Nes-cre)1Wmz page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Nes-cre)1Wmz expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Nes   Mutation details: The transgene consists of a cre cDNA immediately 3' of the Nes transcription start site. The Nes promoter drives expression of the cre gene and includes 5.8 kb of upstream promoter sequences and 3.2 kb of downstream sequences (containing the first 2 introns). The Nes promoter is active in neural progenitor cells and somites. (J:79917)

Activity:	Tissue activity of this recombinase allele
Driver:	Nes (species not specified) Summary of all recombinase alleles driven by Nes. Comparative matrix view of recombinase activities

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

10 assay results 1 RNA-Seq or microarray experiment(s)

List all tumor models in MMHCdb carrying Tg(Nes-cre)1Wmz

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:79917 Petersen PH, et al., Progenitor cell maintenance requires numb and numblike during mouse neurogenesis. Nature. 2002 Oct 31;419(6910):929-34
All:	35 reference(s)