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Cacnb2tm1Rgg
Targeted Allele Detail
Summary
Symbol: Cacnb2tm1Rgg
Name: calcium channel, voltage-dependent, beta 2 subunit; targeted mutation 1, Ronald G Gregg
MGI ID: MGI:2429694
Synonyms: beta2-null, Cavbeta2-
Gene: Cacnb2  Location: Chr2:14607899-14992719 bp, + strand  Genetic Position: Chr2, 10.7 cM
Alliance: Cacnb2tm1Rgg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:80080
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    The gene was disrupted by replacement of exons 4-13 with a PGK-neo cassette. (J:80080)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cacnb2 Mutation:  50 strains or lines available
References
Original:  J:80080 Ball SL, et al., Role of the beta(2) subunit of voltage-dependent calcium channels in the retinal outer plexiform layer. Invest Ophthalmol Vis Sci. 2002 May;43(5):1595-603
All:  6 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory