Slc4a1tm1Ahc
Targeted Allele Detail
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| Symbol: |
Slc4a1tm1Ahc |
| Name: |
solute carrier family 4 (anion exchanger), member 1; targeted mutation 1, Athar H Chishti |
| MGI ID: |
MGI:2441657 |
| Synonyms: |
band 3-/- |
| Gene: |
Slc4a1 Location: Chr11:102239646-102256107 bp, - strand Genetic Position: Chr11, 66.29 cM, cytoband D
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| Alliance: |
Slc4a1tm1Ahc page
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutation: |
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Insertion
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Mutation details: A neomycin selection cassette was inserted into exon 3. The insertion disrupted the coding region 12 codons downstream of the erythroid-specific start codon. While no protein was detected in red blood cells obtained from homozygous mutant mice, translation of the kidney specific isoform, which is initiated from a start codon downstream of the inserted neo cassette, was verified by Western blot analysis of kidney lysates.
(J:35637)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Slc4a1 Mutation: |
54 strains or lines available
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| Original: |
J:35637 Southgate CD, et al., Targeted disruption of the murine erythroid band 3 gene results in spherocytosis and severe haemolytic anaemia despite a normal membrane skeleton. Nat Genet. 1996 Oct;14(2):227-30 |
| All: |
4 reference(s) |
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Analysis Tools
