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Mir124a-1hg Gene Detail
Summary
  • Symbol
    Mir124a-1hg
  • Name
    Mir124-1 host gene (non-protein coding)
  • Synonyms
    A930011O12Rik, Rncr3
  • Feature Type
    lncRNA gene
  • IDs
    MGI:2442197
    NCBI Gene: 268755
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:64825564-64831410 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 33.77 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    134 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442197
 lncRNA gene Chr14:64824744-64831410 (+)
129S1/SvImJ MGP_129S1SvImJ_G0005562
 lincRNA gene Chr14:59149829-59156473 (+)
A/J MGP_AJ_G0005547
 lincRNA gene Chr14:57798122-57804953 (+)
AKR/J MGP_AKRJ_G0005526
 lincRNA gene Chr14:59824783-59831411 (+)
BALB/cJ MGP_BALBcJ_G0005529
 lincRNA gene Chr14:57746022-57753113 (+)
C3H/HeJ MGP_C3HHeJ_G0005475
 lincRNA gene Chr14:59459245-59465884 (+)
C57BL/6NJ MGP_C57BL6NJ_G0005686
 lincRNA gene Chr14:61903853-61912362 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0005053
 lincRNA gene Chr14:55737201-55743860 (+)
CAST/EiJ MGP_CASTEiJ_G0005418
 lincRNA gene Chr14:55940326-55946967 (+)
CBA/J MGP_CBAJ_G0005465
 lincRNA gene Chr14:63779034-63785669 (+)
DBA/2J MGP_DBA2J_G0005480
 lincRNA gene Chr14:57462709-57469358 (+)
FVB/NJ MGP_FVBNJ_G0005506
 lincRNA gene Chr14:56858414-56865225 (+)
LP/J MGP_LPJ_G0005565
 lincRNA gene Chr14:60184765-60191404 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0005492
 lincRNA gene Chr14:62938535-62947443 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0005684
 lincRNA gene Chr14:58989498-58996543 (+)
PWK/PhJ MGP_PWKPhJ_G0005368
 lincRNA gene Chr14:54148291-54155089 (+)
SPRET/EiJ MGP_SPRETEiJ_G0005286
 lincRNA gene Chr14:54950817-54957443 (+)
WSB/EiJ MGP_WSBEiJ_G0005468
 lincRNA gene Chr14:59303870-59311728 (+)



Homology
more
  • Human Ortholog
    MIR124-1HG, MIR124-1 host gene
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR124-1HG, MIR124-1 host gene
  • Synonyms
    LINC00599, neuroLNC, Rncr3
  • Links
    NCBI Gene ID: 157627

  • Chr Location
    8p23.1; chr8:9899871-9919233 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 1 allele in 2 genetic backgrounds
    7 phenotypes from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted mutation exhibit impaired hippocampal axogenesis and retinal cone cell survival.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    720
  • Tissues
    12
  • cDNA Data
    99
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      35
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 268755 NCBI Gene Model | MGI Sequence Detail 5847 C57BL/6J ±  kb
    transcript NR_040709 RefSeq | MGI Sequence Detail 4054 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 99
      cDNA 99

      Microarray probesets 3
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 6
      Gene Ontology 3
      Phenotypes 8
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:349888 Zhang J, et al., m(5)C methylated lncRncr3-MeCP2 interaction restricts miR124a-initiated neurogenesis. Nat Commun. 2024 Jun 15;15(1):5136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory