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Clptm1l Gene Detail
Summary
  • Symbol
    Clptm1l
  • Name
    CLPTM1-like
  • Synonyms
    C130052I12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442892
    NCBI Gene: 218335
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:73752125-73768724 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 40.12 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    485 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442892
 protein coding gene Chr13:73752121-73768758 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020747
 protein coding gene Chr13:74060048-74076685 (+)
A/J MGP_AJ_G0020703
 protein coding gene Chr13:71424423-71441060 (+)
AKR/J MGP_AKRJ_G0020677
 protein coding gene Chr13:73670213-73686850 (+)
BALB/cJ MGP_BALBcJ_G0020700
 protein coding gene Chr13:71916917-71933554 (+)
C3H/HeJ MGP_C3HHeJ_G0020494
 protein coding gene Chr13:73348072-73364709 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021137
 protein coding gene Chr13:76535063-76551700 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018704
 protein coding gene Chr13:68243794-68260618 (+)
CAST/EiJ MGP_CASTEiJ_G0020011
 protein coding gene Chr13:72426655-72443318 (+)
CBA/J MGP_CBAJ_G0020453
 protein coding gene Chr13:79375706-79392343 (+)
DBA/2J MGP_DBA2J_G0020578
 protein coding gene Chr13:71247246-71263883 (+)
FVB/NJ MGP_FVBNJ_G0020558
 protein coding gene Chr13:70266926-70283563 (+)
LP/J MGP_LPJ_G0020651
 protein coding gene Chr13:74308433-74325083 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020586
 protein coding gene Chr13:77811466-77828102 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021176
 protein coding gene Chr13:72979541-72996178 (+)
PWK/PhJ MGP_PWKPhJ_G0019765
 protein coding gene Chr13:69980659-69997331 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019588
 protein coding gene Chr13:69434846-69451516 (+)
WSB/EiJ MGP_WSBEiJ_G0020069
 protein coding gene Chr13:73523214-73539848 (+)



Homology
more
  • Human Ortholog
    CLPTM1L, CLPTM1 like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CLPTM1L, CLPTM1 like
  • Synonyms
    CRR9
  • Links
    NCBI Gene ID: 81037
    neXtProt AC: NX_Q96KA5
    UniProt: Q96KA5

  • Chr Location
    5p15.33; chr5:1317752-1345099 (-)  GRCh38
Human Diseases
more
  • Diseases
    11 with human CLPTM1L associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit partial prenatal and neonatal lethality; however, surviving mice are fertile and overtly normal with no significant alterations in the development, maturation and differentiation of B-lymphocytes or production of antibodies by antibody secreting cells.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    711
  • Tissues
    3
  • cDNA Data
    103
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000021610 Ensembl Gene Model | MGI Sequence Detail 16600 C57BL/6J ±  kb
    transcript ENSMUST00000022102 Ensembl | MGI Sequence Detail 2340 Not Applicable  
    polypeptide ENSMUSP00000022102 Ensembl | MGI Sequence Detail 539 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 104
      cDNA 103
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 3
      Gene Ontology 5
      Phenotypes 13
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory