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Ptgs2os Gene Detail
Summary
  • Symbol
    Ptgs2os
  • Name
    prostaglandin-endoperoxide synthase 2, opposite strand
  • Synonyms
    7530420F21Rik
  • Feature Type
    lncRNA gene
  • IDs
    MGI:2443180
    NCBI Gene: 320019
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:149950624-149975625 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 63.84 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    904 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443180
lncRNA gene Chr1:149950624-149975714 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015118
unclassified non-coding RNA gene Chr1:154710424-154740502 (-)
A/J MGP_AJ_G0015091
unclassified non-coding RNA gene Chr1:148450582-148484143 (-)
AKR/J MGP_AKRJ_G0015054
unclassified non-coding RNA gene Chr1:152981181-153014295 (-)
BALB/cJ MGP_BALBcJ_G0015054
unclassified non-coding RNA gene Chr1:149013424-149038666 (-)
C3H/HeJ MGP_C3HHeJ_G0014877
unclassified non-coding RNA gene Chr1:153186907-153215807 (-)
C57BL/6NJ MGP_C57BL6NJ_G0015511
unclassified non-coding RNA gene Chr1:160048064-160079411 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0013257
unclassified non-coding RNA gene Chr1:140787085-140811804 (-)
CAST/EiJ MGP_CASTEiJ_G0014432
unclassified non-coding RNA gene Chr1:152617417-152643447 (-)
CBA/J MGP_CBAJ_G0014856
unclassified non-coding RNA gene Chr1:165730091-165765027 (-)
DBA/2J MGP_DBA2J_G0014949
unclassified non-coding RNA gene Chr1:147520398-147545584 (-)
FVB/NJ MGP_FVBNJ_G0014961
unclassified non-coding RNA gene Chr1:145960260-145985720 (-)
LP/J MGP_LPJ_G0015032
unclassified non-coding RNA gene Chr1:155712525-155742485 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0014987
unclassified non-coding RNA gene Chr1:173408030-173453400 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0015549
unclassified non-coding RNA gene Chr1:152810430-152837972 (-)
PWK/PhJ MGP_PWKPhJ_G0014224
unclassified non-coding RNA gene Chr1:146448466-146477419 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014012
unclassified non-coding RNA gene Chr1:151461318-151538684 (-)
WSB/EiJ MGP_WSBEiJ_G0014535
unclassified non-coding RNA gene Chr1:152909729-152938776 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    3 phenotypes from multigenic genotypes
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit increased susceptibility to LPS-induced lung inflammation.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    • All Sequences
    • RefSeq
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 320019 NCBI Gene Model | MGI Sequence Detail 25002 C57BL/6J ±  kb
    transcript NR_015466 RefSeq | MGI Sequence Detail 2994 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 6
    References
    more
    • Summaries
      All 12
      Gene Ontology 1
      Phenotypes 3
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:325487 Robinson EK, et al., lincRNA-Cox2 Functions to Regulate Inflammation in Alveolar Macrophages during Acute Lung Injury. J Immunol. 2022 Apr 15;208(8):1886-1900

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    11/19/2024
    MGI 6.24
    The Jackson Laboratory