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Manea Gene Detail
Summary
  • Symbol
    Manea
  • Name
    mannosidase, endo-alpha
  • Synonyms
    4932703L02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444484
    NCBI Gene: 242362
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:26324506-26346891 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 10.92 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    939 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444484
 protein coding gene Chr4:26324506-26346913 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028105
 protein coding gene Chr4:23447361-23469503 (-)
A/J MGP_AJ_G0028063
 protein coding gene Chr4:22778331-22803056 (-)
AKR/J MGP_AKRJ_G0028028
 protein coding gene Chr4:23299035-23321165 (-)
BALB/cJ MGP_BALBcJ_G0028074
 protein coding gene Chr4:22846388-22868778 (-)
C3H/HeJ MGP_C3HHeJ_G0027804
 protein coding gene Chr4:23472991-23496319 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028517
 protein coding gene Chr4:24476742-24501364 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025859
 protein coding gene Chr4:21096645-21119615 (-)
CAST/EiJ MGP_CASTEiJ_G0027259
 protein coding gene Chr4:23137337-23162431 (-)
CBA/J MGP_CBAJ_G0027777
 protein coding gene Chr4:25133536-25156204 (-)
DBA/2J MGP_DBA2J_G0027920
 protein coding gene Chr4:22699067-22721520 (-)
FVB/NJ MGP_FVBNJ_G0027886
 protein coding gene Chr4:22275454-22295371 (-)
LP/J MGP_LPJ_G0028029
 protein coding gene Chr4:23566810-23593407 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027919
 protein coding gene Chr4:26867457-26907858 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028576
 protein coding gene Chr4:23238317-23260474 (-)
PWK/PhJ MGP_PWKPhJ_G0026979
 protein coding gene Chr4:22364801-22387682 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026807
 protein coding gene Chr4:23029974-23051705 (-)
WSB/EiJ MGP_WSBEiJ_G0027336
 protein coding gene Chr4:23211707-23236538 (-)



Homology
more
  • Human Ortholog
    MANEA, mannosidase endo-alpha
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MANEA, mannosidase endo-alpha
  • Synonyms
    ENDO, hEndo
  • Links
    NCBI Gene ID: 79694
    neXtProt AC: NX_Q5SRI9
    UniProt: Q5SRI9

  • Chr Location
    6q16.1; chr6:95577485-95609470 (+)  GRCh38
Human Diseases
more
  • Diseases
    3 with human MANEA associations

Human Disease Mouse Models
      
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    31
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040520 Ensembl Gene Model | MGI Sequence Detail 22386 C57BL/6J ±  kb
transcript ENSMUST00000041374 Ensembl | MGI Sequence Detail 4867 Not Applicable  
polypeptide ENSMUSP00000038671 Ensembl | MGI Sequence Detail 462 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 31
    cDNA 31

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory