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Tg(Mpz-cre)1Brn
Transgene Detail
Summary
Symbol: Tg(Mpz-cre)1Brn
Name: transgene insertion 1, Anton Berns
MGI ID: MGI:2445228
Synonyms: P0A-Cre, P0 Cre, POCreA, Tg(P0-Cre)1Gth
Transgene: Tg(Mpz-cre)1Brn  Location: unknown  
Alliance: Tg(Mpz-cre)1Brn page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Mpz-cre)1Brn expression driven by 1 gene
 
Mutation detailsThis transgene expresses Cre recombinase under the control of a rat Mpz promoter. This promoter is active in many, but not all, myelinating Schwann cells. (J:80158)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Mpz (rat)
Summary of all recombinase alleles driven by Mpz.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Tumor Data
List all tumor models in MMHCdb carrying Tg(Mpz-cre)1Brn
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
Four founders were originally designated as P0CreA-D.
References
Original:  J:80158 Akagi K, et al., Cre-mediated somatic site-specific recombination in mice. Nucleic Acids Res. 1997 May 1;25(9):1766-73
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory