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Tg(COL2A1-cre)1Wag
Transgene Detail
Summary
Symbol: Tg(COL2A1-cre)1Wag
Name: transgene insertion 1, Erwin F Wagner
MGI ID: MGI:2445431
Synonyms: Col2-Cre, collagen2a1-cre
Transgene: Tg(COL2A1-cre)1Wag  Location: unknown  
Alliance: Tg(COL2A1-cre)1Wag page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(COL2A1-cre)1Wag expression driven by 1 gene
 
Mutation details: This transgene expresses cre recombinase under the control of human COL2A1 promoter and enhancer sequences. Human COL2A1 promoter and enhancer sequences drive transgene expression. Transgene expression is observed in chondrogenic tissues, the developing eye, epidermis, heart myocardium, and endoderm of the developing yolk sac. (J:60838)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: COL2A1 (human)
Summary of all recombinase alleles driven by COL2A1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 13 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:60838 Haigh JJ, et al., Conditional inactivation of VEGF-A in areas of collagen2a1 expression results in embryonic lethality in the heterozygous state. Development. 2000 Apr;127(7):1445-53
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory