Suv39h1tm1Jnw
Targeted Allele Detail
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| Symbol: |
Suv39h1tm1Jnw |
| Name: |
suppressor of variegation 3-9 1; targeted mutation 1, Thomas Jenuwein |
| MGI ID: |
MGI:2445449 |
| Gene: |
Suv39h1 Location: ChrX:7927410-7940999 bp, - strand Genetic Position: ChrX, 3.64 cM, cytoband A1-A2
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| Alliance: |
Suv39h1tm1Jnw page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:72503
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| Parent Cell Line: |
Other (see notes) (ES Cell)
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| Strain of Origin: |
129
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| Allele Type: |
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Targeted (Null/knockout, Reporter) |
| Mutation: |
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Insertion
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Mutation details: The endogenous locus was disrupted after codon 40 by homologous recombination of a construct containing lacZ followed by RSV-neo. No protein was detected in homozygous mutant mice by Western blot analysis of testis nuclear extracts. Beta-galactosidase activity was reported in mutant mice.
(J:72503)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Suv39h1 Mutation: |
10 strains or lines available
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ES cell line = E14.1 (129P2/OlaHsd) or R1 ((129X1/SvJ x 129S1/Sv)F1-Kitl+).
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| Original: |
J:72503 Peters AH, et al., Loss of the suv39h histone methyltransferases impairs Mammalian heterochromatin and genome stability. Cell. 2001 Nov 2;107(3):323-37 |
| All: |
18 reference(s) |
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Analysis Tools
