Gabrr1tm1Nsp
Targeted Allele Detail
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| Symbol: |
Gabrr1tm1Nsp |
| Name: |
gamma-aminobutyric acid type A receptor subunit rho 1; targeted mutation 1, Neal S Peachy |
| MGI ID: |
MGI:2446461 |
| Synonyms: |
GABAc rho1 null, Gabrr1tm1Mmc |
| Gene: |
Gabrr1 Location: Chr4:33132556-33163606 bp, + strand Genetic Position: Chr4, 14.68 cM
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| Alliance: |
Gabrr1tm1Nsp page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:76682
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| Parent Cell Line: |
HM-1 (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd-Hprt1b-m3
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A neomycin selection cassette replaced exons 2-9 by homologous recombination. Immunohistochemistry analysis on retina demonstrated that ablation of this subunit resulted in the absence of all GABA-C immunoreactivity.
(J:76682)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Gabrr1 Mutation: |
34 strains or lines available
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| Original: |
J:76682 McCall MA, et al., Elimination of the rho1 subunit abolishes GABA(C) receptor expression and alters visual processing in the mouse retina. J Neurosci. 2002 May 15;22(10):4163-74 |
| All: |
9 reference(s) |
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Analysis Tools
