About   Help   FAQ
Tg(Gata1-cre)1Sho
Transgene Detail
Summary
Symbol: Tg(Gata1-cre)1Sho
Name: transgene insertion 1, Stuart Orkin
MGI ID: MGI:2446599
Synonyms: GATA1-Cre
Transgene: Tg(Gata1-cre)1Sho  Location: unknown  
Alliance: Tg(Gata1-cre)1Sho page
Transgene
origin
Strain of Origin:  CD-1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Gata1-cre)1Sho expression driven by 1 gene
 
Mutation details: Sequence encoding cre recombinase was adjoined to the murine Gata1 promoter region. The expanded expression pattern (relative to the endogenous Gata1 gene) has been attributed to leaky cre expression during an early stage of embryogenesis. While the Gata1 promoter was putatively a hematopoietic-specific promoter, efficient cre mediated excision has been observed in germ cells. (J:64291)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gata1 (mouse)
Summary of all recombinase alleles driven by Gata1.
 

Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 20 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:64291 Mao X, et al., Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice. Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):5037-42
All:  26 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory