Foxo1tm1Whb
Targeted Allele Detail
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| Symbol: |
Foxo1tm1Whb |
| Name: |
forkhead box O1; targeted mutation 1, William H Biggs III |
| MGI ID: |
MGI:2447732 |
| Synonyms: |
Foxo1-, FoxO1+ |
| Gene: |
Foxo1 Location: Chr3:52175758-52257530 bp, + strand Genetic Position: Chr3, 23.19 cM
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| Alliance: |
Foxo1tm1Whb page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:79560
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Null/knockout, Reporter) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The endogenous locus was disrupted by a beta-geo cassette inserted immediately downstream of the start codon in exon 1 by homologous recombination. The deleted region included the coding region of exon 1 and approximately 3 kb of intronic sequnence. Transcript was undetected by RT-PCR analysis of homozygous mutant embryos.
(J:79560)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Foxo1 Mutation: |
32 strains or lines available
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| Original: |
J:79560 Nakae J, et al., Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1. Nat Genet. 2002 Oct;32(2):245-53 |
| All: |
11 reference(s) |
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Analysis Tools
