Nrg1<tm3Cbm> Targeted Allele Detail MGI Mouse (MGI:2447761)

Nrg1^tm3Cbm
Targeted Allele Detail

Summary

Symbol:	Nrg1^tm3Cbm
Name:	neuregulin 1; targeted mutation 3, Carmen Birchmeier
MGI ID:	MGI:2447761
Synonyms:	nrg-1^f, nrg-1^flox
Gene:	Nrg1 Location: Chr8:32299493-33381858 bp, - strand Genetic Position: Chr8, 18.75 cM
Alliance:	Nrg1^tm3Cbm page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:69623
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Mutation
description

Allele Type:		Targeted (Conditional ready, No functional change)
Mutation:		Insertion
		A floxed allele was generated that contained loxP sites inserted into intron 6 and in intron 9. (J:69623)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:

4 assay results
1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Nrg1 Mutation:	54 strains or lines available

References

Original:	J:69623 Yang X, et al., Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation. Neuron. 2001 May;30(2):399-410
All:	22 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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