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Dleu7 Gene Detail
Summary
  • Symbol
    Dleu7
  • Name
    deleted in lymphocytic leukemia, 7
  • Synonyms
    MGC:47306
  • Feature Type
    protein coding gene
  • IDs
    MGI:2447771
    NCBI Gene: 239133
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:62513678-62530428 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 33.19 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    576 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2447771
 protein coding gene Chr14:62513678-62530496 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021444
 protein coding gene Chr14:56704723-56724774 (-)
A/J MGP_AJ_G0021403
 protein coding gene Chr14:55445989-55464316 (-)
AKR/J MGP_AKRJ_G0021379
 protein coding gene Chr14:57428414-57447129 (-)
BALB/cJ MGP_BALBcJ_G0021409
 protein coding gene Chr14:55399214-55416515 (-)
C3H/HeJ MGP_C3HHeJ_G0021186
 protein coding gene Chr14:57047274-57068572 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021848
 protein coding gene Chr14:59433406-59452345 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019388
 protein coding gene Chr14:53415622-53432355 (-)
CAST/EiJ MGP_CASTEiJ_G0020703
 protein coding gene Chr14:53469623-53488588 (-)
CBA/J MGP_CBAJ_G0021153
 protein coding gene Chr14:61165914-61188211 (-)
DBA/2J MGP_DBA2J_G0021276
 protein coding gene Chr14:55119194-55136357 (-)
FVB/NJ MGP_FVBNJ_G0021255
 protein coding gene Chr14:54523749-54544592 (-)
LP/J MGP_LPJ_G0021351
 protein coding gene Chr14:57750796-57768703 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021284
 protein coding gene Chr14:60473942-60502826 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021871
 protein coding gene Chr14:56567733-56590020 (-)
PWK/PhJ MGP_PWKPhJ_G0020447
 protein coding gene Chr14:51785779-51806037 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020280
 protein coding gene Chr14:52537177-52560522 (-)
WSB/EiJ MGP_WSBEiJ_G0020756
 protein coding gene Chr14:56885537-56906676 (-)



Homology
more
  • Human Ortholog
    DLEU7, deleted in lymphocytic leukemia 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DLEU7, deleted in lymphocytic leukemia 7
  • Links
    NCBI Gene ID: 220107
    neXtProt AC: NX_Q6UYE1
    UniProt: Q6UYE1

  • Chr Location
    13q14.3; chr13:50519364-50843939 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    19
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    13
  • Targeted
    3
  • Genomic Mutations
    2 involving Dleu7
  • Find Mice (IMSR)
    7 strains or lines available
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    735
  • Tissues
    8
  • cDNA Data
    6
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 239133 NCBI Gene Model | MGI Sequence Detail 16751 C57BL/6J ±  kb
transcript NM_173419 RefSeq | MGI Sequence Detail 1348 C57BL/6  
polypeptide Q8CHZ8 UniProt | EBI | MGI Sequence Detail 209 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 2
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Diseases 1
    Phenotypes 11
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory