About   Help   FAQ
Ccnd3tm1Pisc
Targeted Allele Detail
Summary
Symbol: Ccnd3tm1Pisc
Name: cyclin D3; targeted mutation 1, Piotr Sicinski
MGI ID: MGI:2448172
Synonyms: D3-
Gene: Ccnd3  Location: Chr17:47815976-47910614 bp, + strand  Genetic Position: Chr17, 23.37 cM
Alliance: Ccnd3tm1Pisc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:80994
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: A 1.4 kb genomic fragment encompassing exons 1 and 2 was replaced with a neomycin selection cassette inserted by homologous recombination. Protein was undetected by Western blot analysis of homozygous mutant embryo lysates. (J:88120)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 11 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccnd3 Mutation:  507 strains or lines available
References
Original:  J:80994 Ciemerych MA, et al., Development of mice expressing a single D-type cyclin. Genes Dev. 2002 Dec 15;16(24):3277-89
All:  30 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory