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H3c15 Gene Detail
Summary
  • Symbol
    H3c15
  • Name
    H3 clustered histone 15
  • Synonyms
    H3-614, Hist2h3c2, Hist2h3c2-ps, Hist2h3ca1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448357
    NCBI Gene: 97114
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:96145424-96146300 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 3, 41.69 cM, cytoband F1-F2
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    116 from dbSNP Build 142
  • Strain Annotations
    8
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448357
protein coding gene Chr3:96145424-96146443 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0027576
protein coding gene Chr3:94034205-94034689 (+)
AKR/J MGP_AKRJ_G0027540
protein coding gene Chr3:96213559-96214246 (+)
BALB/cJ MGP_BALBcJ_G0027586
protein coding gene Chr3:93822708-93823351 (+)
C3H/HeJ MGP_C3HHeJ_G0027316
protein coding gene Chr3:96498363-96523140 (+)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0026771
protein coding gene Chr3:95836109-95837494 (+)
CBA/J no annotation
DBA/2J MGP_DBA2J_G0027436
protein coding gene Chr3:93335030-93336015 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0027540
protein coding gene Chr3:98367020-98367767 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    H3C13, H3 clustered histone 13
  • Vertebrate Orthologs
    14
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    H3C13, H3 clustered histone 13
  • Synonyms
    H3C14, H3C15, HIST2H3D
  • Links
    NCBI Gene ID: 653604
    neXtProt AC: NX_Q71DI3
    UniProt: Q71DI3

  • Chr Location
    1q21.2; chr1:149813225-149813693 (-)  GRCh38

  • Human Ortholog
    H3C14, H3 clustered histone 14
  • Synonyms
    H3, H3.2, H3C13, H3C15, H3F2, H3FM, H3FN, H3/M, HIST2H3C
  • Links
    NCBI Gene ID: 126961
    neXtProt AC: NX_Q71DI3
    UniProt: Q71DI3

  • Chr Location
    1q21.2

  • Human Ortholog
    H3C15, H3 clustered histone 15
  • Synonyms
    H3C13, H3C14, H3/n, H3/o, HIST2H3A
  • Links
    NCBI Gene ID: 333932
    neXtProt AC: NX_Q71DI3
    UniProt: Q71DI3

  • Chr Location
    1q21.2; chr1:149852608-149853125 (+)  GRCh38

  • Human Ortholog
    H3C8, H3 clustered histone 8
  • Synonyms
    H3C1, H3C10, H3C11, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3FH, H3/h, HIST1H3G
  • Links
    NCBI Gene ID: 8355
    neXtProt AC: NX_P68431
    UniProt: P68431

  • Chr Location
    6p22.2; chr6:26270918-26271413 (-)  GRCh38

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving H3c15
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 97114 NCBI Gene Model | MGI Sequence Detail 877 C57BL/6J ±  kb
transcript NM_054045 RefSeq | MGI Sequence Detail 877 C57BL/6  
polypeptide P84228 UniProt | EBI | MGI Sequence Detail 136 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • GlyGen
    P84228 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2140105, MGI:6325017
References
more
  • Summaries
    All 25
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:8574 Taylor JD, et al., Sequences of four mouse histone H3 genes: implications for evolution of mouse histone genes. J Mol Evol. 1986;23(3):242-9
  • Latest
    J:332290 Vetrivel S, et al., Identification of ocular regulatory functions of core histone variant H3.2. Exp Eye Res. 2022 Dec 15;226:109346

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory