Pcyox1tm1Sgy
Targeted Allele Detail
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| Symbol: |
Pcyox1tm1Sgy |
| Name: |
prenylcysteine oxidase 1; targeted mutation 1, Stephen G Young |
| MGI ID: |
MGI:2449567 |
| Synonyms: |
Pcly -, Pcyox1tm1Abe |
| Gene: |
Pcyox1 Location: Chr6:86362988-86374132 bp, - strand Genetic Position: Chr6, 37.69 cM
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| Alliance: |
Pcyox1tm1Sgy page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:79474
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129S4/SvJae
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP-flanked neomycin selection cassette replaced exon 6, which encodes the carboxy-terminus of the protein. Northern blot analysis on RNA derived from various tissues of homozygous mice demonstrated that truncated transcripts were expressed from this allele.
(J:79474)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Pcyox1 Mutation: |
26 strains or lines available
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| Original: |
J:79474 Beigneux A, et al., Prenylcysteine lyase deficiency in mice results in the accumulation of farnesylcysteine and geranylgeranylcysteine in brain and liver. J Biol Chem. 2002 Oct 11;277(41):38358-63 |
| All: |
3 reference(s) |
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Analysis Tools
