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Zfxtm1Dcp
Targeted Allele Detail
Summary
Symbol: Zfxtm1Dcp
Name: zinc finger protein X-linked; targeted mutation 1, David C Page
MGI ID: MGI:2450147
Gene: Zfx  Location: ChrX:93118237-93167308 bp, - strand  Genetic Position: ChrX, 41.48 cM, cytoband D
Alliance: Zfxtm1Dcp page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:41131
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 7 through 10 were replaced by a neomycin selection cassette inserted by homologous recombination. The deleted region encoded half of the acidic domain and the nuclear localiztion signal. (J:41131)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 assay results
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zfx Mutation:  33 strains or lines available
References
Original:  J:41131 Luoh SW, et al., Zfx mutation results in small animal size and reduced germ cell number in male and female mice. Development. 1997 Jun;124(11):2275-84
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory