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Tg(Dspp-cre)1Kul
Transgene Detail
Summary
Symbol: Tg(Dspp-cre)1Kul
Name: transgene insertion 1, Ashok B Kulkarni
MGI ID: MGI:2450281
Synonyms: Dspp-Cre
Transgene: Tg(Dspp-cre)1Kul  Location: unknown  
Alliance: Tg(Dspp-cre)1Kul page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Dspp-cre)1Kul expression driven by 1 gene
 
Mutation details: 6 kb of mouse Dspp promoter sequences were used to drive expression of cre recombinase in teeth. Transgene expression in odontoblasts was confirmed by immunohistochemical analysis of cross sections from 30 old transgenic mice. (J:81653)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Dspp (mouse)
Summary of all recombinase alleles driven by Dspp.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Notes
Transgenic line E displayed tooth-specific transgene expression and was used for further characterization and analysis.
References
Original:  J:81653 Sreenath TL, et al., Odontoblast-specific expression of cre recombinase successfully deletes gene segments flanked by loxp sites in mouse teeth. Genesis. 2003 Feb;35(2):94-9
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory