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Tg(KRT18-cre/ERT2)1Rgo
Transgene Detail
Summary
Symbol: Tg(KRT18-cre/ERT2)1Rgo
Name: transgene insertion 1, Robert G Oshima
MGI ID: MGI:2450291
Synonyms: K18CreER, K18iresCreERT2
Transgene: Tg(KRT18-cre/ERT2)1Rgo  Location: unknown  
Alliance: Tg(KRT18-cre/ERT2)1Rgo page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(KRT18-cre/ERT2)1Rgo expression driven by 1 gene
 
Mutation details: The transgenic construct encodes a tamoxifen-inducible fusion protein consisting of cre recombinase and a mutated human estrogen receptor ligand-binding domain inserted into exon 7 of human KRT18. Human KRT18 regulatory sequences were used to drive transgene expression in epithelial cells. (J:81652)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: KRT18 (human)
Summary of all recombinase alleles driven by KRT18.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Tumor Data
List all tumor models in MMHCdb carrying Tg(KRT18-cre/ERT2)1Rgo
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:81652 Wen F, et al., Expression of conditional cre recombinase in epithelial tissues of transgenic mice. Genesis. 2003 Feb;35(2):100-6
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory