Tg(CD2-cre)1Tjw
Transgene Detail
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| Symbol: |
Tg(CD2-cre)1Tjw |
| Name: |
transgene insertion 1, Trevor J Wilson |
| MGI ID: |
MGI:2450356 |
| Synonyms: |
CD2-Cre, CD2Cre |
| Transgene: |
Tg(CD2-cre)1Tjw Location: unknown
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| Alliance: |
Tg(CD2-cre)1Tjw page
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(CD2-cre)1Tjw expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Homolog in Mouse |
Note |
| human |
CD2 (914) |
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Mutation details: The transgene consists of a modified cre recombinase gene fused to exon 1 of a human CD2 minigene just upstream of the translation initiation codon. The human CD2 promoter was used to drive transgene expression in T lymphocytes. The cre recombinase sequence was modified to include a nuclear localization signal and a modified KOZAK consensus sequence. Transgene expression was confirmed by immunohistochemical analysis of thymus and spleen from transgenic animals.
(J:81648)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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CD2
(human)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Two transgenic founders displaying similar cre expression patterns were created.
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| Original: |
J:81648 Wilson TJ, et al., A human CD2 minigene directs CRE-mediated recombination in T cells in vivo. Genesis. 2002 Aug;33(4):181-4 |
| All: |
2 reference(s) |
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Analysis Tools
