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Tg(NPHS2-cre)295Lbh
Transgene Detail
Summary
Symbol: Tg(NPHS2-cre)295Lbh
Name: transgene insertion 295, Lawrence B Holzman
MGI ID: MGI:2450359
Synonyms: 2.5P-Cre, NPHS2.Cre, pod-Cre, podocin-Cre, PodoCre, Tg(NPHS2-cre)1Lbh
Transgene: Tg(NPHS2-cre)295Lbh  Location: unknown  
Alliance: Tg(NPHS2-cre)295Lbh page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F2
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(NPHS2-cre)295Lbh expression driven by 1 gene
 
Mutation detailsThe human NPHS2 promoter, including the entire 5' untranslated region, was used to drive cre recombinase expression in podocytes. (J:81633)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: NPHS2 (human)
Summary of all recombinase alleles driven by NPHS2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Notes
24 transgenic founders were created. Phenotypic analysis was performed on founder line #295.
References
Original:  J:81633 Moeller MJ, et al., Podocyte-specific expression of cre recombinase in transgenic mice. Genesis. 2003 Jan;35(1):39-42
All:  209 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory