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Neurog2tm1(cre/Esr1*)And
Targeted Allele Detail
Summary
Symbol: Neurog2tm1(cre/Esr1*)And
Name: neurogenin 2; targeted mutation 1, David J Anderson
MGI ID: MGI:2652037
Synonyms: Neurog2-CreER, Neurog2tm1(cre/ESR1)And, Ngn2-, Ngn2-CreERTM
Gene: Neurog2  Location: Chr3:127426784-127429280 bp, + strand  Genetic Position: Chr3, 56.54 cM, cytoband H1
Alliance: Neurog2tm1(cre/Esr1*)And page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77104
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Neurog2tm1(cre/Esr1*)And expression driven by 1 gene
 
Mutation details: A gene expressing a tamoxifen-inducible form of Cre recombinase was inserted into the Neurog2 gene. A mutated form of a Cre-murine estrogen receptor 1 fusion protein is expressed under the control of the Neurog2 gene. (J:77104)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Neurog2 (mouse)
Summary of all recombinase alleles driven by Neurog2.
 

Expression
In Mice Carrying this Mutation: 6 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Neurog2 Mutation:  18 strains or lines available
References
Original:  J:77104 Zirlinger M, et al., Transient expression of the bHLH factor neurogenin-2 marks a subpopulation of neural crest cells biased for a sensory but not a neuronal fate. Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8084-9
All:  16 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory