Cd5l<tm1Nto> Targeted Allele Detail MGI Mouse (MGI:2653296)

Cd5l^tm1Nto
Targeted Allele Detail

Summary

Symbol:	Cd5l^tm1Nto
Name:	CD5 antigen-like; targeted mutation 1, Makoto Naito
MGI ID:	MGI:2653296
Synonyms:	AIM^-
Gene:	Cd5l Location: Chr3:87265188-87278380 bp, + strand Genetic Position: Chr3, 38.19 cM
Alliance:	Cd5l^tm1Nto page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:82352
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutation:		Insertion
		Mutation details: Exon 3 was disrupted by a neomycin selection cassette inserted by homologous recombination. The disrupted region encoded the second scavenger receptor cysteine-rich (SRCR) domain. (J:52195, J:82352)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Cd5l Mutation:	30 strains or lines available

References

Original:	J:82352 Kuwata K, et al., AIM inhibits apoptosis of T cells and NKT cells in Corynebacterium-induced granuloma formation in mice. Am J Pathol. 2003 Mar;162(3):837-47
All:	15 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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