Rr133tm1Eno
Targeted Allele Detail
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| Symbol: |
Rr133tm1Eno |
| Name: |
regulatory region 133; targeted mutation 1, Eric N Olson |
| MGI ID: |
MGI:2653307 |
| Synonyms: |
BAenh-, Delta neoBAenh, Hand2BA, Hand2tm1Eno |
| Gene: |
Rr133 Location: unknown Genetic Position: Chr8, Syntenic
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| Alliance: |
Rr133tm1Eno page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:81764
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| Parent Cell Line: |
SM1 (ES Cell)
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| Strain of Origin: |
129S6/SvEvTac
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| Allele Type: |
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Targeted (Modified regulatory region, Null/knockout) |
| Mutation: |
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Intragenic deletion
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Mutation details: A 754 bp region, containing the 208 bp branchial arch enhancer upstream of the Hand2 gene, was replaced with a loxP site flanked neomycin resistance gene cassette, which was removed through subsequent cre-mediated recombination. Whole mount in situ hybridization of homozygous mutant embryos showed a lack of endogenous transcript in the ventrolateral portions of the first and second branchial arches.
(J:81764)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Rr133 Mutation: |
0 strains or lines available
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| Original: |
J:81764 Yanagisawa H, et al., Targeted deletion of a branchial arch-specific enhancer reveals a role of dHAND in craniofacial development. Development. 2003 Mar;130(6):1069-78 |
| All: |
7 reference(s) |
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Analysis Tools
