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Tg(Nphs1-cre)1Seq
Transgene Detail
Summary
Symbol: Tg(Nphs1-cre)1Seq
Name: transgene insertion 1, Susan E Quaggin
MGI ID: MGI:2653994
Synonyms: Neph-cre, PC1, Tg(Neph1-cre)1Seq
Transgene: Tg(Nphs1-cre)1Seq  Location: unknown  
Alliance: Tg(Nphs1-cre)1Seq page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Nphs1-cre)1Seq expression driven by 1 gene
 
Mutation details: A mouse Neph1 promoter fused to a cre recombinase gene was used for the transgene. A 4.125 kb fragment of the mouse Neph1 promoter was used to drive transgene expression in podocytes. (J:82024)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nphs1 (mouse)
Summary of all recombinase alleles driven by Nphs1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:82024 Eremina V, et al., Glomerular-specific gene excision in vivo. J Am Soc Nephrol. 2002 Mar;13(3):788-93
All:  9 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory