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Foxh1tm1.1Hmd
Targeted Allele Detail
Summary
Symbol: Foxh1tm1.1Hmd
Name: forkhead box H1; targeted mutation 1.1, Hiroshi Hamada
MGI ID: MGI:2654232
Synonyms: Foxh1-
Gene: Foxh1  Location: Chr15:76552425-76554148 bp, - strand  Genetic Position: Chr15, 36.24 cM
Alliance: Foxh1tm1.1Hmd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:69593
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation details: This allele is derived from Foxh1tm1Hmd. Mutant animals were bred to cre-expressing line Tg(ACTB-cre)13Miya to delete exon 2 and the neo cassette. Homozygous mutant embryos did not express gene transcripts as determined by Northern blot and RT-PCR analysis. (J:69593)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 49 assay results
In Structures Affected by this Mutation: 10 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Foxh1 Mutation:  34 strains or lines available
References
Original:  J:69593 Yamamoto M, et al., The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse. Genes Dev. 2001 May 15;15(10):1242-56
All:  5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory