Epha4<tm1Kldr> Targeted Allele Detail MGI Mouse (MGI:2654411)

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Epha4^tm1Kldr
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Epha4^tm1Kldr
Name:	Eph receptor A4; targeted mutation 1, Klas Kullander
MGI ID:	MGI:2654411
Synonyms:	Eph4^tm1Oki
Gene:	Epha4 Location: Chr1:77343822-77491725 bp, - strand Genetic Position: Chr1, 39.55 cM, cytoband C1-C5
Alliance:	Epha4^tm1Kldr page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:82479
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Mutation
description

Allele Type:		Targeted (Null/knockout, Reporter)
Mutations:		Insertion, Intragenic deletion
		Exon 3 was replaced with a cassette containing beta-galactosidase cDNA fused to the tau gene. (J:82479)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Epha4 Mutation:	67 strains or lines available

References

Original:	J:82479 Kullander K, et al., Role of EphA4 and EphrinB3 in local neuronal circuits that control walking. Science. 2003 Mar 21;299(5614):1889-92
All:	4 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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