Tg(Lck-cre)3785Nik Transgene Detail MGI Mouse (MGI:2655481)

Tg(Lck-cre)3785Nik
Transgene Detail

Summary

Symbol:	Tg(Lck-cre)3785Nik
Name:	transgene insertion 3785, Nigel Killeen
MGI ID:	MGI:2655481
Synonyms:	dLck-hcre³⁷⁸⁵
Transgene:	Tg(Lck-cre)3785Nik Location: unknown
Alliance:	Tg(Lck-cre)3785Nik page

Transgene
origin

Strain of Origin:

(C57BL/6 x DBA/2)F2

Transgene
description

Transgene Type:

Transgenic (Recombinase)

Mutation:

Insertion

Tg(Lck-cre)3785Nik expression driven by 1 gene

Mutation details: This transgene expresses the codon-improved cre recombinase (icre) open reading frame under the control of the distal Lck promoter (dLck). This transgene is expressed in T cells, after the preTCR signal has been delivered. (J:73479, J:99042)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lck (species not specified) Summary of all recombinase alleles driven by Lck.

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

This transgene is used in J:73479, but specific details are published in J:99042.

References

Original:	J:73479 Wang Q, et al., Homeostatic competition among T cells revealed by conditional inactivation of the mouse Cd4 gene. J Exp Med. 2001 Dec 17;194(12):1721-30
All:	3 reference(s)

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