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Ilktm2Ref
Targeted Allele Detail
Summary
Symbol: Ilktm2Ref
Name: integrin linked kinase; targeted mutation 2, Reinhard Fassler
MGI ID: MGI:2655774
Synonyms: Ilk-
Gene: Ilk  Location: Chr7:105385799-105392132 bp, + strand  Genetic Position: Chr7, 55.97 cM, cytoband E1
Alliance: Ilktm2Ref page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:82761
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsLoxP sites were introduced into exon 1 and intron 2. Transient expression of cre recombinase in correctly targeted ES cells facilicated the removal of the floxed region (part of exon 1 and entire exon 2). (J:82761)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ilk Mutation:  18 strains or lines available
References
Original:  J:82761 Sakai T, et al., Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation. Genes Dev. 2003 Apr 1;17(7):926-40
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory