Dync1h1<Cra1> Chemically induced Allele Detail MGI Mouse (MGI:2661085)

Dync1h1^Cra1
Chemically induced Allele Detail

Summary

Symbol:	Dync1h1^Cra1
Name:	dynein cytoplasmic 1 heavy chain 1; cramping 1
MGI ID:	MGI:2661085
Synonyms:	Cra, Cra1
Gene:	Dync1h1 Location: Chr12:110567886-110633379 bp, + strand Genetic Position: Chr12, 60.7 cM
Alliance:	Dync1h1^Cra1 page

Mutation
origin

Strain of Origin:

C3HeB/FeJ

Mutation
description

Allele Type:		Chemically induced (ENU)
Mutation:		Single point mutation
		Mutation details: Cra1 was found to be allelic to Loa through complementation testing. The mutation in the Cra mouse was identified as A to G mutation that results in the amino acid convertion tyrosine 1055 to a cysteine (Y1055C). (J:83128)
Inheritance:		Dominant

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Dync1h1 Mutation:	195 strains or lines available

References

Original:	J:68708 Hrabe de Angelis MH, et al., Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat Genet. 2000 Aug;25(4):444-7
All:	10 reference(s)

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