Dync1h1<Cra1> Chemically induced Allele Detail MGI Mouse (MGI:2661085)

Dync1h1^Cra1
Chemically induced Allele Detail

Summary

Symbol:	Dync1h1^Cra1
Name:	dynein cytoplasmic 1 heavy chain 1; cramping 1
MGI ID:	MGI:2661085
Synonyms:	Cra, Cra1
Gene:	Dync1h1 Location: Chr12:110567886-110633379 bp, + strand Genetic Position: Chr12, 60.7 cM
Alliance:	Dync1h1^Cra1 page

Mutation
origin

Strain of Origin:

C3HeB/FeJ

Mutation
description

Allele Type:		Chemically induced (ENU)
Mutation:		Single point mutation
		Mutation details: Cra1 was found to be allelic to Loa through complementation testing. The mutation in the Cra mouse was identified as A to G mutation that results in the amino acid convertion tyrosine 1055 to a cysteine (Y1055C). (J:83128)
Inheritance:		Dominant

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Dync1h1 Mutation:	195 strains or lines available

References

Original:	J:68708 Hrabe de Angelis MH, et al., Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat Genet. 2000 Aug;25(4):444-7
All:	10 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24