Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol:	Tg(Gfap-cre)2Brn
Name:	transgene insertion 2, Anton Berns
MGI ID:	MGI:2663939
Synonyms:	GFAP-Cre, GFAP/Cre, mGFAP-Cre
Transgene:	Tg(Gfap-cre)2Brn  Location: unknown
Alliance:	Tg(Gfap-cre)2Brn page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Gfap-cre)2Brn expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Gfap (MGI:95697)   Mutation details: Transgene expressing bacteriophage P1 Cre recombinase under control of the mouse Gfap promoter. This transgene is expressed in the developing forebrain and in the spinal ganglia and also in scattered precursor cells located in the EGL of the cerebellum. (J:61961)

Activity:	Tissue activity of this recombinase allele
Driver:	Gfap (mouse) Summary of all recombinase alleles driven by Gfap. Comparative matrix view of recombinase activities Alliance mouse Gfap gene page

View phenotypes and curated references for all genotypes (concatenated display).

List all tumor models in MMHCdb carrying Tg(Gfap-cre)2Brn

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:61961 Marino S, et al., Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum. Genes Dev. 2000 Apr 15;14(8):994-1004
All:	11 reference(s)