About   Help   FAQ
Serpinf1tm1Craw
Targeted Allele Detail
Summary
Symbol: Serpinf1tm1Craw
Name: serine (or cysteine) peptidase inhibitor, clade F, member 1; targeted mutation 1, Susan E Crawford
MGI ID: MGI:2664515
Synonyms: PEDF null
Gene: Serpinf1  Location: Chr11:75300855-75313449 bp, - strand  Genetic Position: Chr11, 45.87 cM
Alliance: Serpinf1tm1Craw page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:83748
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: A genomic fragment encompassing exons 3 through 6 was replaced with a cassette containing IRES-lacZ followed by floxed neo. (J:83748)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 10 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Serpinf1 Mutation:  28 strains or lines available
References
Original:  J:83748 Doll JA, et al., Pigment epithelium-derived factor regulates the vasculature and mass of the prostate and pancreas. Nat Med. 2003 Jun;9(6):774-80
All:  12 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory