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Slc8a2tm1(cre)Hssh
Targeted Allele Detail
Summary
Symbol: Slc8a2tm1(cre)Hssh
Name: solute carrier family 8 (sodium/calcium exchanger), member 2; targeted mutation 1, Hee-Sup Shin
MGI ID: MGI:2667136
Synonyms: NCX2-
Gene: Slc8a2  Location: Chr7:15863751-15894988 bp, + strand  Genetic Position: Chr7, 8.75 cM
Alliance: Slc8a2tm1(cre)Hssh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:84050
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Slc8a2tm1(cre)Hssh expression driven by 1 gene
 
Mutation details: The coding region of exon 1 was replaced with a cassette containing nls-cre and neo. Protein was undetected by Western blot analysis of homozygous mutant mice. Expression of cre was verified by Northern blot analysis and the observed recombination of a reporter transgene. (J:84050)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Slc8a2 (mouse)
Summary of all recombinase alleles driven by Slc8a2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc8a2 Mutation:  43 strains or lines available
References
Original:  J:84050 Jeon D, et al., Enhanced learning and memory in mice lacking Na+/Ca2+ exchanger 2. Neuron. 2003 Jun 19;38(6):965-76
All:  8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory