Grik5tm1Cont
Targeted Allele Detail
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| Symbol: |
Grik5tm1Cont |
| Name: |
glutamate receptor, ionotropic, kainate 5 (gamma 2); targeted mutation 1, Anis Contractor |
| MGI ID: |
MGI:2668206 |
| Synonyms: |
KA2- |
| Gene: |
Grik5 Location: Chr7:24709274-24771771 bp, - strand Genetic Position: Chr7, 13.73 cM
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| Alliance: |
Grik5tm1Cont page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:81742
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129S/SvEv
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Sequence encompassing two full exons and a portion of a third, collectively encoding membrane domains I and II, were replaced with a neomycin selection cassette inserted by homologous recombination. Normal protein was undetected by immunohistochemical analysis of homozygous mutant hippocampal sections.
(J:81742)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Grik5 Mutation: |
50 strains or lines available
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| Original: |
J:81742 Contractor A, et al., Loss of kainate receptor-mediated heterosynaptic facilitation of mossy-fiber synapses in KA2-/- mice. J Neurosci. 2003 Jan 15;23(2):422-9 |
| All: |
13 reference(s) |
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Analysis Tools
