Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol: Zfp423nur12 Name: zinc finger protein 423; neurological 12 MGI ID: MGI:2671784 Synonyms: ataxia1, nurm12Jus Gene: Zfp423  Location: Chr8:88388438-88686223 bp, - strand  Genetic Position: Chr8, 42.29 cM, cytoband C4 Alliance: Zfp423nur12 page

Ataxia and malformation in Zfp423nur12/Zfp423nur12 mice Show the 1 phenotype image(s) involving this allele.

Strain of Origin:	C57BL/6J
Project Collection:	Mutagenesis for Dev. Defects

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: This phenotypic mutant was identified in an ENU mutagenesis screen at the Baylor College of Medicine. A C-to-T transition mutation in the fourth exon results in the introduction of a premature stop codon. Western blot analysis showed that no detectable protein was expressed from this allele. (J:114758) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	50 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Zfp423 Mutation:	274 strains or lines available

Original:	J:85113 Kile BT, et al., Functional genetic analysis of mouse chromosome 11. Nature. 2003 Sep 4;425(6953):81-6
All:	8 reference(s)