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Hmga1tm1Cha
Targeted Allele Detail
Summary
Symbol: Hmga1tm1Cha
Name: high mobility group AT-hook 1; targeted mutation 1, Kirin Chada
MGI ID: MGI:2673322
Synonyms: Hmga1+/-
Gene: Hmga1  Location: Chr17:27775471-27782648 bp, + strand  Genetic Position: Chr17, 14.5 cM
Alliance: Hmga1tm1Cha page
Mutation
origin
Mouse Generated:  Earliest citation of chimera generation: J:84851
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Inactivation of this locus precluded germline transmission and therefore mice carrying this allele are chimeras. The coding regions of exons 3 through 6 were replaced with a neomycin selection cassette inserted by homologous recombination. (J:84851)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hmga1 Mutation:  23 strains or lines available
References
Original:  J:84851 Liu J, et al., Hmga1 is required for normal sperm development. Mol Reprod Dev. 2003 Sep;66(1):81-9
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory