Atp6v1b1<tm1Choo> Targeted Allele Detail MGI Mouse (MGI:2673510)

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Atp6v1b1^tm1Choo
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Atp6v1b1^tm1Choo
Name:	ATPase, H+ transporting, lysosomal V1 subunit B1; targeted mutation 1, Daniel Choo
MGI ID:	MGI:2673510
Synonyms:	Atp6b1^-, Atp6v1b1-, Atp6v1b1^tm1Rpl
Gene:	Atp6v1b1 Location: Chr6:83719999-83735837 bp, + strand Genetic Position: Chr6, 35.94 cM
Alliance:	Atp6v1b1^tm1Choo page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:84744
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutations:		Insertion, Intragenic deletion
		Exons 7 through 11 were replaced with a neomycin selection cassette. (J:84744, J:101414)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Atp6v1b1 Mutation:	32 strains or lines available

References

Original:	J:84744 Dou H, et al., Mice lacking the B1 subunit of H+ -ATPase have normal hearing. Hear Res. 2003 Jun;180(1-2):76-84
All:	17 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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