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Jak3tm1Jni
Targeted Allele Detail
Summary
Symbol: Jak3tm1Jni
Name: Janus kinase 3; targeted mutation 1, James N Ihle
MGI ID: MGI:2675061
Synonyms: Jak3 -
Gene: Jak3  Location: Chr8:72129027-72143221 bp, + strand  Genetic Position: Chr8, 34.43 cM
Alliance: Jak3tm1Jni page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:29723
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details: A hygromycin selection gene was inserted into the first coding exon. No encoded protein was detected in extracts derived from spleen, thymus, or bone marrow. (J:29723)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Jak3 Mutation:  84 strains or lines available
References
Original:  J:29723 Nosaka T, et al., Defective lymphoid development in mice lacking Jak3. Science. 1995 Nov 3;270(5237):800-2
All:  14 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory