Ccne1<tm1Pisc> Targeted Allele Detail MGI Mouse (MGI:2675473)

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Ccne1^tm1Pisc
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Ccne1^tm1Pisc
Name:	cyclin E1; targeted mutation 1, Piotr Sicinski
MGI ID:	MGI:2675473
Synonyms:	Cyclin E1^-
Gene:	Ccne1 Location: Chr7:37797409-37806915 bp, - strand Genetic Position: Chr7, 25.35 cM
Alliance:	Ccne1^tm1Pisc page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:85224
Parent Cell Line:	D3 (ES Cell)
Strain of Origin:	129S2/SvPas

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutations:		Insertion, Intragenic deletion
		Coding exons 2-11 were replaced with a neomycin resistance gene. (J:85224)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Ccne1 Mutation:	23 strains or lines available

References

Original:	J:85224 Geng Y, et al., Cyclin E ablation in the mouse. Cell. 2003 Aug 22;114(4):431-43
All:	13 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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