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Mir155 Gene Detail
Summary
  • Symbol
    Mir155
  • Name
    microRNA 155
  • Synonyms
    Mirn155, mmu-mir-155
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676840
    NCBI Gene: 387173
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:84511028-84511092 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 46.92 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    98 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676840
 miRNA gene Chr16:84511028-84511092 (+)
129S1/SvImJ MGP_129S1SvImJ_G0008293
 miRNA gene Chr16:85287256-85287320 (+)
A/J MGP_AJ_G0008281
 miRNA gene Chr16:81404806-81404870 (+)
AKR/J MGP_AKRJ_G0008264
 miRNA gene Chr16:83795963-83796027 (+)
BALB/cJ MGP_BALBcJ_G0008266
 miRNA gene Chr16:81860629-81860693 (+)
C3H/HeJ MGP_C3HHeJ_G0008208
 miRNA gene Chr16:84371807-84371871 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008461
 miRNA gene Chr16:88055206-88055270 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007520
 miRNA gene Chr16:79349913-79349977 (+)
CAST/EiJ MGP_CASTEiJ_G0008077
 miRNA gene Chr16:84820140-84820204 (+)
CBA/J MGP_CBAJ_G0008177
 miRNA gene Chr16:91812193-91812257 (+)
DBA/2J MGP_DBA2J_G0008210
 miRNA gene Chr16:81282528-81282592 (+)
FVB/NJ MGP_FVBNJ_G0008234
 miRNA gene Chr16:80481271-80481335 (+)
LP/J MGP_LPJ_G0008292
 miRNA gene Chr16:84973266-84973330 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0008198
 miRNA gene Chr16:96259685-96259749 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008451
 miRNA gene Chr16:84267364-84267428 (+)
PWK/PhJ MGP_PWKPhJ_G0007998
 miRNA gene Chr16:81441196-81441260 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007887
 miRNA gene Chr16:83774350-83774414 (+)
WSB/EiJ MGP_WSBEiJ_G0008156
 miRNA gene Chr16:84523252-84523316 (+)



Homology
more
  • Human Ortholog
    MIR155, microRNA 155
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR155, microRNA 155
  • Synonyms
    mir-155, MIRN155, miRNA155
  • Links
    NCBI Gene ID: 406947

  • Chr Location
    chr21:25573980-25574044 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with Mir155 mouse models; 4 with human MIR155 associations

Human Disease Mouse Models
      
IDs
 View 1 model
      
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    8 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    66 phenotypes from 9 alleles in 10 genetic backgrounds
    3 images
    542 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for this loss-of-function/reporter allele are viable and fertile, with the lacZ reporter allowing detection of bic/Mirn155 promoter transcriptional activity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    711
  • Tissues
    5
  • cDNA Data
    2
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      25
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 387173 NCBI Gene Model | MGI Sequence Detail 65 C57BL/6J ±  kb
    transcript NR_029565 RefSeq | MGI Sequence Detail 65 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 2
      Primer pair 1
      Other 2

      Microarray probesets 1
    Other Database
    Links
    less
    miRBase MI0000177
    References
    more
    • Summaries
      All 649
      Developmental Gene Expression 4
      Diseases 8
      Gene Ontology 7
      Phenotypes 542
    • Earliest
      J:30229 Davisson MT, et al., Segmental trisomy as a mouse model for Down syndrome. Prog Clin Biol Res. 1993;384:117-33
    • Latest
      J:354984 Emili M, et al., Reversal of neurodevelopmental impairment and cognitive enhancement by pharmacological intervention with the polyphenol polydatin in a Down syndrome model. Neuropharmacology. 2024 Sep 27;261:110170
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory