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Mir15a Gene Detail
Summary
  • Symbol
    Mir15a
  • Name
    microRNA 15a
  • Synonyms
    Mirn15a, mmu-mir-15a
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676841
    NCBI Gene: 387174
  • Member of
    Mirc30 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:61869476-61869559 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 33.16 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    41 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676841
 miRNA gene Chr14:61869476-61869559 (-)
129S1/SvImJ MGP_129S1SvImJ_G0008128
 miRNA gene Chr14:56023919-56024002 (-)
A/J MGP_AJ_G0008115
 miRNA gene Chr14:54800844-54800927 (-)
AKR/J MGP_AKRJ_G0008093
 miRNA gene Chr14:56757242-56757325 (-)
BALB/cJ MGP_BALBcJ_G0008097
 miRNA gene Chr14:54754922-54755005 (-)
C3H/HeJ MGP_C3HHeJ_G0008041
 miRNA gene Chr14:56386883-56386966 (-)
C57BL/6NJ MGP_C57BL6NJ_G0008287
 miRNA gene Chr14:58752125-58752208 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0007378
 miRNA gene Chr14:52771620-52771703 (-)
CAST/EiJ MGP_CASTEiJ_G0007919
 miRNA gene Chr14:52782125-52782208 (-)
CBA/J MGP_CBAJ_G0008009
 miRNA gene Chr14:60444440-60444523 (-)
DBA/2J MGP_DBA2J_G0008045
 miRNA gene Chr14:54459312-54459395 (-)
FVB/NJ MGP_FVBNJ_G0008068
 miRNA gene Chr14:53883627-53883710 (-)
LP/J MGP_LPJ_G0008128
 miRNA gene Chr14:57056113-57056196 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0008037
 miRNA gene Chr14:59757448-59757531 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0008283
 miRNA gene Chr14:55901547-55901630 (-)
PWK/PhJ MGP_PWKPhJ_G0007841
 miRNA gene Chr14:51131064-51131147 (-)
SPRET/EiJ MGP_SPRETEiJ_G0007736
 miRNA gene Chr14:51826228-51826311 (-)
WSB/EiJ MGP_WSBEiJ_G0007996
 miRNA gene Chr14:56218845-56218928 (-)



Homology
more
  • Human Ortholog
    MIR15A, microRNA 15a
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR15A, microRNA 15a
  • Synonyms
    hsa-mir-15a, mir-15a, MIRN15A, miRNA15A
  • Links
    NCBI Gene ID: 406948

  • Chr Location
    chr13:50049119-50049201 (-)  GRCh38
Human Diseases
less
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Mir15a
  • Find Mice (IMSR)
    3 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    740
  • Tissues
    21
  • Literature Summary
    16
Sequences &
Gene Models
less
  • All Sequences
    24
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 387174 NCBI Gene Model | MGI Sequence Detail 84 C57BL/6J ±  kb
transcript NR_029733 RefSeq | MGI Sequence Detail 84 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 9
    Primer pair 5
    Other 4
Other Database
Links
less
miRBase MI0000564
References
more
  • Summaries
    All 66
    Developmental Gene Expression 16
    Diseases 2
    Gene Ontology 8
    Phenotypes 8
  • Earliest
    J:84907 Lagos-Quintana M, et al., Identification of tissue-specific microRNAs from mouse. Curr Biol. 2002 Apr 30;12(9):735-9
  • Latest
    J:354576 Zhou C, et al., Loss of microRNA-15a/16-1 function promotes neuropathological and functional recovery in experimental traumatic brain injury. JCI Insight. 2024 Jun 24;9(12)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory