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Mir23b Gene Detail
Summary
  • Symbol
    Mir23b
  • Name
    microRNA 23b
  • Synonyms
    Mirn23b, mmu-mir-23b
Location &
Maps
more
  • Sequence Map
    Chr13:63448298-63448371 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 32.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    88 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676898
 miRNA gene Chr13:63448298-63448371 (+)
129S1/SvImJ MGP_129S1SvImJ_G0008077
 miRNA gene Chr13:63260577-63260650 (+)
A/J MGP_AJ_G0008067
 miRNA gene Chr13:60958743-60958816 (+)
AKR/J MGP_AKRJ_G0008046
 miRNA gene Chr13:63000878-63000951 (+)
BALB/cJ MGP_BALBcJ_G0008050
 miRNA gene Chr13:61387175-61387248 (+)
C3H/HeJ MGP_C3HHeJ_G0007993
 miRNA gene Chr13:62533093-62533166 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008235
 miRNA gene Chr13:65321327-65321400 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007338
 miRNA gene Chr13:58632886-58632959 (+)
CAST/EiJ MGP_CASTEiJ_G0007876
 miRNA gene Chr13:62536081-62536154 (+)
CBA/J MGP_CBAJ_G0007962
 miRNA gene Chr13:67842048-67842121 (+)
DBA/2J MGP_DBA2J_G0007996
 miRNA gene Chr13:60801667-60801740 (+)
FVB/NJ MGP_FVBNJ_G0008018
 miRNA gene Chr13:59919000-59919073 (+)
LP/J MGP_LPJ_G0008079
 miRNA gene Chr13:63537387-63537460 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0007988
 miRNA gene Chr13:66815257-66815330 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008233
 miRNA gene Chr13:62305516-62305589 (+)
PWK/PhJ MGP_PWKPhJ_G0007797
 miRNA gene Chr13:60359981-60360054 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007692
 miRNA gene Chr13:60460827-60460900 (+)
WSB/EiJ MGP_WSBEiJ_G0007948
 miRNA gene Chr13:62795727-62795800 (+)



Homology
more
  • Human Ortholog
    MIR23B, microRNA 23b
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR23B, microRNA 23b
  • Synonyms
    hsa-mir-23b, mir-23b, MIRN23B, miRNA23B
  • Links
    NCBI Gene ID: 407011

  • Chr Location
    chr9:95085208-95085304 (+)  GRCh38
Human Diseases
more
  • Diseases
    2 with human MIR23B associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Targeted
    2
  • Genomic Mutations
    3 involving Mir23b
  • Find Mice (IMSR)
    4 strains or lines available
Mice homozygous for a targeted deletion are viable with no observed pathologies.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    9
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    791
  • Tissues
    56
  • Literature Summary
    15
Sequences &
Gene Models
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  • All Sequences
    23
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 387217 NCBI Gene Model | MGI Sequence Detail 74 C57BL/6J ±  kb
transcript NR_029530 RefSeq | MGI Sequence Detail 74 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 8
    Primer pair 2
    Other 6
Other Database
Links
less
miRBase MI0000141
References
more
  • Summaries
    All 44
    Developmental Gene Expression 15
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:350807 Ishibashi S, et al., Myelin-Specific microRNA-23a/b Cluster Deletion Inhibits Myelination in the Central Nervous System during Postnatal Growth and Aging. Genes (Basel). 2024 Mar 25;15(4)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory