About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:65636 Ito S, et al., Molecular cloning and expression analyses of mouse betaklotho, which encodes a novel klotho family protein. Mech Dev. 2000 Nov;98(1-2):115-9
Assay type: RNA in situ
MGI Accession ID: MGI:2676993
Gene symbol: Klb
Gene name: klotho beta
Probe: beta-kl cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: yolk sac Present 3A
TS17: liver Present Regionally restricted 3A Expression is in the hepatocytes and is absent in the hematopoietic cell clusters.

Specimen 3B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: liver Strong 3B
TS20: gut Present Regionally restricted 3B Expression is in the gut epithelium.

Specimen 3C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: liver Strong 3C
TS23: gut Present Regionally restricted 3C Expression is in the gut epithelium.
TS23: pancreas body parenchyma Present 3C Expression is in the acinar cells of the pancreas.
TS23: pancreas head parenchyma Present 3C Expression is in the acinar cells of the pancreas.
TS23: pancreas tail parenchyma Present 3C Expression is in the acinar cells of the pancreas.
TS23: trunk mesenchyme Present Regionally restricted 3C Expression is in the preadipocytes in the cervical brown adipose tissue.

Specimen 3D: embryonic day 19.5 (more )
Structure Level Pattern Image Note
TS26: skin Strong Regionally restricted 3D Expression is in the subcutaneous white adipose tisue.

Specimen 4A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: yolk sac endoderm Strong 4A
TS17: liver Present Regionally restricted 4A Expression is in the hepatocytes and is absent in the hematopoietic cell clusters.
TS17: extraembryonic component Present Regionally restricted 4A Expression is in the extraembryonic mesodermal components and lower levels were found in the Reichert's membrane. Absent in the aminon and blood islands.

Specimen 4B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: yolk sac Present 4B
TS17: liver Present Regionally restricted 4B Expression is in the hepatocytes and is absent in the hematopoietic cell clusters.

Specimen 4C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: liver Strong 4C
TS20: gut Present Regionally restricted 4C Expression is in the gut epithelium.

Specimen 4D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: liver Strong 4D
TS20: gut Present Regionally restricted 4D Expression is in the gut epithelium.

Specimen 4E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: pancreas body parenchyma Strong Regionally restricted 4E Expression is in the acinar cells of the pancreas.
TS23: pancreas head parenchyma Strong Regionally restricted 4E Expression is in the acinar cells of the pancreas.
TS23: pancreas tail parenchyma Strong Regionally restricted 4E Expression is in the acinar cells of the pancreas.

Specimen 4F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: trunk mesenchyme Strong Regionally restricted 4F Expression is in the cervical brown adipose tissue.

Specimen 4G: embryonic day 19.5 (more )
Structure Level Pattern Image Note
TS26: skin Strong Regionally restricted 4G Expression is in the white and brown adipose tissue. The expression in the white adipose tissue is stronger.
TS26: trunk mesenchyme Strong Regionally restricted 4G Expression is in the white and brown adipose tissue. The expression in the white adipose tissue is stronger.

Specimen 4H: embryonic day 19.5 (more )
Structure Level Pattern Image Note
TS26: skin Strong Regionally restricted 4H Expression is in the subcutaneous white adipose tisue.

Specimen 4I: embryonic day 19.5 (more )
Structure Level Pattern Image Note
TS26: trunk mesenchyme Present Regionally restricted 4I Expression is in the white adipose tissue surrounding the vertebrae.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
09/17/2024
MGI 6.24
The Jackson Laboratory